Sun W, Chen G, Wang F, Qin Y, Wang Z, Nie J, Ma G. Ecofriendly electrospun membranes loaded with visible-light-responding nanoparticles for multifunctional usages: highly efficient air filtration, dye scavenging, and bactericidal activity. Lv D, Wang R, Tang G, Mou Z, Lei J, Han J, De Smedt S, Xiong R, Huang C. Thermoresponsive cellulose acetate-poly( N-isopropylacrylamide) core-shell fibers for controlled capture and release of moisture. Thakur N, Sargur Ranganath A, Sopiha K, Baji A. Advantages and challenges offered by biofunctional core-shell fiber systems for tissue engineering and drug delivery. Sperling LE, Reis KP, Pranke P, Wendorff JH. Cell-mediated fibre recruitment drives extracellular matrix mechanosensing in engineered fibrillar microenvironments. 2017 3:3563.īaker BM, Trappmann B, Wang WY, Sakar MS, Kim IL, Shenoy VB, Burdick JA, Chen CS. Nano-/microfibrous cotton-wool-like 3d scaffold with core-shell architecture by emulsion electrospinning for skin tissue regeneration. Pal P, Srivas PK, Dadhich P, Das B, Maulik D, Dhara S. Biodegradable fibrous scaffolds with tunable properties formed from photo-cross-linkable poly(glycerol sebacate). Ifkovits JL, Devlin JJ, Eng G, Martens TP, Vunjak-Novakovic G, Burdick JA. Bioinspired multifunctional hybrid hydrogel promotes wound healing. Accelerated wound healing by injectable microporous gel scaffolds assembled from annealed building blocks. Griffin DR, Weaver WM, Scumpia PO, Di Carlo D, Segura T. Expression of cardiac proteins in neonatal cardiomyocytes on PGS/fibrinogen core/shell substrate for cardiac tissue engineering. Ravichandran R, Venugopal JR, Sundarrajan S, Mukherjee S, Sridhar R, Ramakrishna S. Two-dimensional electrospun nanofibrous membranes for promoting random skin flap survival. Sun X, Zheng R, Cheng L, Zhao X, Jin R, Zhang L, Zhang Y, Zhang Y, Cui W. Microfluidic electrospray niacin metal-organic frameworks encapsulated microcapsules for wound healing. It’s worth noting that the percentage of skin tissue was regenerated by 95% within 14 days, which suggests the potential application for electrospun-based synthetic fibrous scaffolds on wound healing.Ĭhen G, Yu Y, Wu X, Wang G, Gu G, Wang F, Ren J, Zhang H, Zhao Y. In addition, the prepared fibers exhibited a strong ability to repair tissues of the skin wound, where the stability of cell security and proliferation, and the lower inflammatory response were all superior to those of pure PLLA scaffold. The core–shell microstructure of fibers was confirmed by TEM and Laser Scanning Confocal Microscopy (LSCM). The fibrous morphology with pores on the surface of the prepared fibers was observed by SEM. In this study, a flexible and cytocompatible poly(glycerol l-lactic acid fibrous scaffold with a core–shell structure was fabricated by coaxial electrospinning, where the shell PLLA was used to be a skeleton with pores on the fibrous surface. Biomimetic scaffolds made by synthetic materials are usually used to replace the natural tissues aimed at speeding up the skin regeneration.
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